Rethinking the role of myeloid-derived suppressor cells in adoptive T-cell therapy for cancer
نویسنده
چکیده
The expansion of cancer-induced myeloid cells is thought to be one of the main obstacles to successful immunotherapy. Nevertheless, in murine tumors undergoing immune-mediated destruction by adoptively transferred T cells, we have recently shown that such cells maintain their immunosuppressive properties. Therefore, adoptive T-cell therapy can, under certain conditions, overcome myeloid cell immunosuppression.
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عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2014